• Mon. Feb 26th, 2024

How Chronic Stress is Linked to Diabetes and Insulin Resistance: A Look at the Molecular Mechanisms


Feb 10, 2024
The connection between war, stress, and the increased risk of diabetes and pre-diabetes

Diabetes is a serious condition that affects millions of people worldwide. Insulin resistance, which occurs when the body is unable to properly use insulin, is a significant risk factor for diabetes. Chronic stress has been linked to insulin resistance, which can negatively impact the body’s ability to regulate blood sugar levels.

A recent review published in January 2022 titled “Molecular Mechanisms Linking Stress and Insulin Resistance” concluded that chronic stress may disrupt the body’s response to insulin, increasing the risk of insulin resistance and diabetes. This disruption can limit the effectiveness of certain diabetes drugs for individuals with diabetes.

Chronic inflammation, caused by prolonged periods of stress, can also contribute to the development of diabetes and worsen related complications such as diabetic neuropathy. Poor sleep quality, which can result from stress and overstimulation, can also contribute to insulin resistance and increase the risk of diabetes.

Research has shown that acute sleep deprivation can reduce insulin sensitivity in healthy individuals without significant changes in cortisol levels. This highlights the critical role that sleep plays in preventing diabetes and maintaining optimal health. Overall, managing chronic stress through lifestyle changes such as exercise, relaxation techniques, and good sleep hygiene may help prevent or delay the onset of diabetes.

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